Feasibility of tumor-informed circulating tumor DNA for detecting minimal residual disease in surgically resected biliary tract cancer

Although limited by the small sample size, our results may indicate a possible role for tumor-informed ctDNA analysis in detecting MRD in surgically resected BTC and warrant further validation in larger studies.

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Publication Details

Journal
PLoS ONE
Published
2026-01-21
DOI
https://doi.org/10.1371/journal.pone.0341432
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Feasibility of tumor-informed circulating tumor DNA for detecting minimal residual disease in surgically resected biliary tract cancer

Hwang-Phil Kim, Dong Soo Kyung, YOUNGHEE PARK, Eun Mi Nam et al.
PLoS ONE
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Feasibility of tumor-informed circulating tumor DNA for detecting minimal residual disease in surgically resected biliary tract cancer

Hwang-Phil Kim, Dong Soo Kyung, YOUNGHEE PARK, Eun Mi Nam, Kyubo Kim, Seog Ki Min, Youngeun Yoo, Hyunji Jo
article en

Abstract

Although limited by the small sample size, our results may indicate a possible role for tumor-informed ctDNA analysis in detecting MRD in surgically resected BTC and warrant further validation in larger studies.

PLoS ONEVol. 21(1)
Ewha Womans University (KR), Nexen (Canada) (CA), Seoul National University Hospital (KR), Seoul National University Bundang Hospital (KR)
National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Good health and well-being
Openalex Percentile: Top 80%
Cholangiocarcinoma and Gallbladder Cancer Studies
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