Low Testosterone in Men With Type 2 Diabetes: The Role of Estrogen Excess and Aromatase Activity
In men with type 2 diabetes, low testosterone is associated with adiposity, glycaemic control, and increased adipose aromatase expression. Relative estrogen excess may contribute to hypothalamic-pituitary-testicular axis suppression and represents a novel target for diagnostic and therapeutic strategies.
Authors
- Fraser W. Gibb (ORCID: https://orcid.org/0000-0002-5576-6463)
- Nyo Nyo Tun
- Dawn E. W. Livingstone
Institutions
- NHS Lothian (GB)
- The Queen's Medical Research Institute (GB)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1111/cen.70098
- Citations
- 1
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 30.73