Odoribacter splanchnicus inhibits toxin production in Clostridioides difficile: insights from clinical correlation and in vitro validation

This work positions <i>O. splanchnicus</i> as a highly promising candidate for the development of next-generation, defined microbial therapeutics and provides a mechanistic foundation for future anti-virulence approaches to combat CDI.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-01-22
DOI
https://doi.org/10.3389/fmicb.2026.1741232
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
0.00
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article

Odoribacter splanchnicus inhibits toxin production in Clostridioides difficile: insights from clinical correlation and in vitro validation

Xianbo Geng, Shujuan Zhang, Changzhong Jin, Nanping Wu et al.
Frontiers in Microbiology
Clostridium difficile and Clostridium perfringens research
article

Odoribacter splanchnicus inhibits toxin production in Clostridioides difficile: insights from clinical correlation and in vitro validation

Xianbo Geng, Shujuan Zhang, Changzhong Jin, Nanping Wu, Na Wang, Zhaoyi Pan, Jing Fan
article en

Abstract

This work positions <i>O. splanchnicus</i> as a highly promising candidate for the development of next-generation, defined microbial therapeutics and provides a mechanistic foundation for future anti-virulence approaches to combat CDI.

Frontiers in MicrobiologyVol. 17
First Affiliated Hospital Zhejiang University (CN)
Openalex Percentile: Top 78%
Clostridium difficile and Clostridium perfringens research
DOIOpen Access PDFOpenAlex
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Odoribacter splanchnicus inhibits toxin production in Clostridioides difficile: insights from clinical correlation and in vitro validation — Xianbo Geng, Shujuan Zhang, et al. · Frontiers in Microbiology (2026) | TGRS Research Map | TGRS