A nationwide genomic surveillance study of Gram-negative bacteria causing community- and hospital-acquired bloodstream infections in China
This first genomic epidemiological investigation of GNB-BSIs stratified by acquisition setting reveals a fundamental clinical and epidemiological divergence between CA- and HA-cases. The study underscores that tracking mortality-associated strains and genes is essential for improving clinical outcomes and advancing etiological knowledge.
Authors
- Jihong Li
- Jingyuan Xi
- Ziyong Sun
- Xuming Li (ORCID: https://orcid.org/0000-0002-5049-9706)
- S. Li
- Dawen Guo
- Mingxiang Zou
- Y M Li
- Xinlan Hu
- Xiaoling Ma
- Fupin Hu
- Li Zhang (ORCID: https://orcid.org/0000-0003-1152-8962)
- Yi Liu (ORCID: https://orcid.org/0000-0002-1058-0382)
- Mei Kang
- Chaolu Hasi
- Xinmiao Jia
- Yingchun Xu
- Bin Shan
- Lijuan Ma
- Yun Xia
- Ping Ji
- Yan Jin
- Long Hu
- Qiwen Yang
- Han Xia
- Tao Xu
- Kang Liao
Institutions
- Hebei Medical University (CN)
- Central South University (CN)
- Nanchang University (CN)
- Xinjiang Medical University (CN)
- Harbin Medical University (CN)
- Sun Yat-sen University (CN)
- Shanxi Medical University (CN)
- Anhui Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- Fudan University (CN)
- Kunming Medical University (CN)
- Peking Union Medical College Hospital (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- West China Hospital of Sichuan University (CN)
- Shaanxi Provincial People's Hospital (CN)
- Second Hospital of Hebei Medical University (CN)
- Capital Institute of Pediatrics (CN)
- Shandong Provincial Hospital (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Anhui Provincial Hospital (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Zhejiang Provincial People's Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Fujian Provincial Hospital (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Huashan Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Tongji Hospital (CN)
- Shanxi Provincial People’s Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Huazhong University of Science and Technology (CN)
- Atotech (United States) (US)
- Chongqing Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Journal of Infection
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1016/j.jinf.2026.106693
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking Union Medical College Hospital
- Peking Union Medical College
- National Science and Technology Major Project
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities