The Effect of Music Exposure on Epileptic Seizures Induced by Pentylenetetrazole in Rats

Under the present experimental conditions, Mozart K.448 did not significantly modulate GABAergic activity as measured by PPI. The observed trends toward shorter seizure latency and higher seizure severity in the music group may reflect a possible context-dependent increase in excitability, although these findings remain preliminary due to the small sample size. Given the complex nature of music's effects, further studies employing larger cohorts, and complementary neurophysiological methods are warranted.

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Publication Details

Journal
Medical Principles and Practice
Published
2026-01-22
DOI
https://doi.org/10.1159/000550550
Primary Topic
Neuroscience and Music Perception
Type
article
Field-Weighted Citation Impact
0.00
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article

The Effect of Music Exposure on Epileptic Seizures Induced by Pentylenetetrazole in Rats

Hilal ADİL, Burcu Çevreli, Erhan Caner Akkaya, Güler Öztürk
Medical Principles and Practice
Neuroscience and Music Perception
article

The Effect of Music Exposure on Epileptic Seizures Induced by Pentylenetetrazole in Rats

Hilal ADİL, Burcu Çevreli, Erhan Caner Akkaya, Güler Öztürk
article en

Abstract

Under the present experimental conditions, Mozart K.448 did not significantly modulate GABAergic activity as measured by PPI. The observed trends toward shorter seizure latency and higher seizure severity in the music group may reflect a possible context-dependent increase in excitability, although these findings remain preliminary due to the small sample size. Given the complex nature of music's effects, further studies employing larger cohorts, and complementary neurophysiological methods are warranted.

Medical Principles and Practice
Üsküdar University (TR), Usak University (TR), Istanbul Medeniyet University (TR)
Openalex Percentile: Top 81%
Neuroscience and Music Perception
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