<i>Lactiplantibacillus plantarum</i> Q180 supplementation restores high-fat diet-induced gut dysbiosis and intestinal barrier dysfunction in mice

LPQ attenuated HFD-induced gut microbial imbalance and intestinal barrier dysfunction, accompanied by reduced systemic endotoxemia. These findings suggest that LPQ may serve as a microbiota-targeted intervention for gut dysbiosis-related metabolic disturbances. Further studies are warranted to validate its long-term and translational potential in humans.