Relationship between lacrimal gland changes and corneal parameters in patients with primary Sjögren’s syndrome and non-Sjögren’s syndrome-related dry eye
SSDE patients experience more corneal epithelial injury, with progressive lacrimal gland changes contributing to corneal nerve damage and inflammation. Multimodal ophthalmic imaging elucidates the interconnected lacrimal gland-corneal neuroimmune dysfunction in SSDE, offering potential diagnostic biomarkers and therapeutic targets for future exploration.
Authors
- Jin Li (ORCID: https://orcid.org/0000-0002-6131-456X)
- Yun Feng
- Haozhe Yu
- Yao Zq
- Xiaojun He
- Chang Liu
- Bo Yang
- Shumin Wang
- Wenyan Zhou
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-22
- DOI
- https://doi.org/10.3389/fmed.2026.1726563
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital
- National Key Research and Development Program of China