Genetic Risk, Healthy Lifestyle, and Risk Stratification for Diverticulitis
Both polygenic risk and lifestyle scores were associated with severe diverticulitis; joint consideration yielded additional information relative to either variable alone. Future personalized profiles may inform shared decision-making discussions about operative intervention.
Authors
- John P. Shelley (ORCID: https://orcid.org/0000-0002-8612-3022)
- Jamie R. Robinson (ORCID: https://orcid.org/0000-0003-0888-0156)
- Richard M. Peek (ORCID: https://orcid.org/0000-0002-4836-5960)
- Thomas E. Ueland (ORCID: https://orcid.org/0000-0001-6618-9318)
- Eric R. Gamazon (ORCID: https://orcid.org/0000-0003-4204-8734)
- Lillias Maguire
- K.W. Sharp
- Alexander T Hawkins
- Jonathan D Mosley
Institutions
- Vanderbilt University (US)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Journal of the American College of Surgeons
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1097/xcs.0000000000001778
- Primary Topic
- Diverticular Disease and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00