Dulaglutide Effect on Proteins Associated With CKD Progression
Six months of dulaglutide treatment significantly lowered concentrations of 14 JKP proteins, particularly those involved in inflammatory and fibrotic pathways. These findings provide insight into biological mechanisms that may underlie the reno-protective effects of dulaglutide.
Authors
- Sok Cin Tye
- Eiichiro Satake (ORCID: https://orcid.org/0000-0002-9784-4423)
- Zaipul I. Md Dom (ORCID: https://orcid.org/0000-0003-3503-7391)
- Brandon E. McFarlin (ORCID: https://orcid.org/0000-0003-3829-4609)
- Kevin L. Duffin (ORCID: https://orcid.org/0000-0002-1656-8982)
- Afton V. Kechter
- Jonathan M. Wilson
- Andrzej S. Krolewski
Institutions
- Joslin Diabetes Center (US)
- Harvard University (US)
- Eli Lilly (United States) (US)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1016/j.ekir.2026.103789
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00