Cardiovascular risk factors and cardiac dysfunction in people with HIV and breast cancer: an observational cohort study in Botswana
Obesity and hypertension are highly prevalent amongst PWH and breast cancer. We also noted a statistically significant, but modest decline in LVEF after cancer therapy initiation. Further studies are needed to prospectively characterize the cardiovascular risk factor burden and changes in cardiac structure and function following cardiotoxic cancer treatment in this population.
Authors
- C D Xia (ORCID: https://orcid.org/0000-0003-0418-0371)
- Thato Moshomo (ORCID: https://orcid.org/0000-0002-8518-8836)
- Yehoda M. Martei (ORCID: https://orcid.org/0000-0002-5631-1567)
- Tlotlo Ralefala (ORCID: https://orcid.org/0000-0003-1150-3722)
- Peter Vuylsteke (ORCID: https://orcid.org/0000-0001-6401-3722)
- Maliha Shaikh
- Henrietta Afari (ORCID: https://orcid.org/0000-0002-5190-4777)
- Scott Dryden‐Peterson (ORCID: https://orcid.org/0000-0002-8487-9731)
- Anran Huang (ORCID: https://orcid.org/0000-0003-1435-1576)
- Julius Mwita
- Sebaga W. Motlhwa
- Bonnie Ky
- Robert Gross
- Mosepele Mosepele
Institutions
- Brigham and Women's Hospital (US)
- Vrije Universiteit Brussel (BE)
- University of Botswana (BW)
- University of California, Los Angeles (US)
- Botswana Harvard AIDS Institute Partnership (BW)
- University of Pennsylvania (US)
Publication Details
- Journal
- Cardio-Oncology
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1186/s40959-025-00417-3
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Pennsylvania
- National Institutes of Health
- Center for AIDS Research, University of Washington