Efficacy and safety of early radiotherapy combined with first-line chemo-immunotherapy in extensive-stage small-cell lung cancer: a multi-center analysis

Early radiotherapy, either thoracic or extra thoracic radiotherapy, combined with first-line chemo-immunotherapy constituted an effective and well-tolerated strategy for patients with ES-SCLC. These findings warrant investigation in prospective randomized trials.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-22
DOI
https://doi.org/10.3389/fimmu.2026.1738352
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy and safety of early radiotherapy combined with first-line chemo-immunotherapy in extensive-stage small-cell lung cancer: a multi-center analysis

R. Meng, Yongling Ji, Yunfeng Wang, Tianle Shen et al.
Frontiers in Immunology
Lung Cancer Research Studies
article

Efficacy and safety of early radiotherapy combined with first-line chemo-immunotherapy in extensive-stage small-cell lung cancer: a multi-center analysis

R. Meng, Yongling Ji, Yunfeng Wang, Tianle Shen, Tongfang Zhou, X. Su, Y. Lu, L. Zhao, X. Fu, Jingyi Jia, Ya Zeng, Bing Xia, Hui Zhu, Zhangru Yang, Xuwei Cai
article en

Abstract

Early radiotherapy, either thoracic or extra thoracic radiotherapy, combined with first-line chemo-immunotherapy constituted an effective and well-tolerated strategy for patients with ES-SCLC. These findings warrant investigation in prospective randomized trials.

Frontiers in ImmunologyVol. 17
Shanghai Chest Hospital (CN), Zhejiang Cancer Hospital (CN), Shandong Tumor Hospital (CN), Wuhan Union Hospital (CN), Cancer Hospital of Chinese Academy of Medical Sciences (CN), Shandong First Medical University (CN), Union Hospital (CN)
National Natural Science Foundation of China, Chinese Society of Clinical Oncology
Good health and well-being
Openalex Percentile: Top 81%
Lung Cancer Research Studies
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