Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts

LLMs can effectively detect potential spin in oncology RCT reporting by identifying discrepancies between how trials are presented in the conclusions vs the full abstracts. This approach could serve as a supplementary tool for improving transparency in scientific reporting, although further development is needed to address more complex trial designs beyond those examined in this feasibility study.

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Publication Details

Journal
JMIR Cancer
Published
2026-01-21
DOI
https://doi.org/10.2196/78221
Citations
2
Primary Topic
Meta-analysis and systematic reviews
Type
article
Field-Weighted Citation Impact
56.17
Controls
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article

Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts

Fabio Dennstädt, Carole Koechli, Christina Schröder, Paul Windisch et al.
2 citations
JMIR Cancer
Meta-analysis and systematic reviews
56.17
article

Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts

Fabio Dennstädt, Carole Koechli, Christina Schröder, Paul Windisch, Daniel M. Aebersold, Robert Förster, Daniel Rudolf Zwahlen
article en
2 citations

Abstract

LLMs can effectively detect potential spin in oncology RCT reporting by identifying discrepancies between how trials are presented in the conclusions vs the full abstracts. This approach could serve as a supplementary tool for improving transparency in scientific reporting, although further development is needed to address more complex trial designs beyond those examined in this feasibility study.

JMIR CancerVol. 12
University of Bern (CH), University Hospital of Bern (CH), Kantonsspital Winterthur (CH)
Quality Education
Openalex Percentile: Top 0%
Meta-analysis and systematic reviews
56.17
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Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts — Fabio Dennstädt, Carole Koechli, et al. · JMIR Cancer (2026) | TGRS Research Map | TGRS