The nocebo effect in psychotherapy

The nocebo effect, negative treatment outcomes arising from patient expectations, therapeutic context, or clinician communication, plays a possibly significant yet often under-estimated role in psychotherapy. Drawing on recent empirical and theoretical contributions, possible mechanisms how nocebo effects occur and can be attenuated in psychotherapeutic practice are discussed. Nocebo effects may arise from therapist communication, previous treatment failures, adverse therapeutic dynamics, poorly managed expectations, social influences outside the therapy, or context-factor elements such as waiting lists. Strategies for mitigating such effects include, for example, empathic engagement, expectation management, and reconditioning of previous negative treatment experiences in clinical settings.

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Publication Details

Journal
Current Opinion in Psychology
Published
2026-01-22
DOI
https://doi.org/10.1016/j.copsyc.2026.102274
Primary Topic
Pain Management and Placebo Effect
Type
article
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article

The nocebo effect in psychotherapy

Andrea W.M. Evers
Current Opinion in Psychology
Pain Management and Placebo Effect
article

The nocebo effect in psychotherapy

Andrea W.M. Evers
article en

Abstract

The nocebo effect, negative treatment outcomes arising from patient expectations, therapeutic context, or clinician communication, plays a possibly significant yet often under-estimated role in psychotherapy. Drawing on recent empirical and theoretical contributions, possible mechanisms how nocebo effects occur and can be attenuated in psychotherapeutic practice are discussed. Nocebo effects may arise from therapist communication, previous treatment failures, adverse therapeutic dynamics, poorly managed expectations, social influences outside the therapy, or context-factor elements such as waiting lists. Strategies for mitigating such effects include, for example, empathic engagement, expectation management, and reconditioning of previous negative treatment experiences in clinical settings.

Current Opinion in PsychologyVol. 69
Leiden University Medical Center (NL)
Openalex Percentile: Top 82%
Pain Management and Placebo Effect
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The nocebo effect in psychotherapy — Andrea W.M. Evers · Current Opinion in Psychology (2026) | TGRS Research Map | TGRS