Metagenomic next-generation sequencing enables early detection and outcome improvement in perioperative mucormycosis after liver transplantation: A single-center experience
mNGS enables earlier detection of perioperative mucormycosis compared to conventional diagnostic methods and supports timely initiation of targeted therapy. Rapid mNGS-guided intervention may prevent progression to disseminated disease and improve prognosis in liver transplant recipients. Integration of mNGS into the diagnostic workflow is recommended for high-risk patients with unexplained pulmonary or cutaneous lesions.
Authors
- Wei Zhang
- Xinyu Yu
- Junfang Liu
- Rongrong Wang
- Ying Chen
- Yuntao Zhang
- Jiameng Qi
- Yue Wu
Institutions
- First People's Hospital of Yuhang District (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1016/j.ijid.2026.108419
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00