Association Between the 2022 AHA/ACC/HFSA Heart Failure Staging and Cardiovascular and Kidney Outcomes in Patients With Diabetes and Kidney Disease: A Post Hoc Analysis of the SCORED Randomized Controlled Trial
Increasing HF stage is associated with a higher risk of HF, major adverse cardiovascular events, and kidney events. Asymptomatic stage B (pre-HF) increased cardiovascular and renal events by >2- and 5-fold, respectively. The benefits of sotagliflozin are consistent, irrespective of HF stage.
Authors
- Benjamin M. Scirica (ORCID: https://orcid.org/0000-0002-7093-7048)
- Julia B. Lewis (ORCID: https://orcid.org/0000-0002-1530-7115)
- Vikas S. Sridhar (ORCID: https://orcid.org/0000-0001-7947-1822)
- Manon Girard
- Darren K. McGuire
- Jacob A. Udell
- Vera A. Bittner
- Phillip Banks
- Bertram Pitt
- David Z I Cherney
- Christopher P Cannon
- Deepak L Bhatt
- Michael Szarek
- Ayodele Odutayo
- Kausik K Ray
- Subodh Verma
- Michael J Davies
- Lawrence A Leiter
Institutions
- Brigham and Women's Hospital (US)
- Parkland Health & Hospital System (US)
- St. Michael's Hospital (CA)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- Inserm (FR)
- Duke University (US)
- Université Paris Cité (FR)
- University of Michigan (US)
- Women's College Hospital (CA)
- Clinical Research Institute (US)
- Lexicon Pharmaceuticals (United States) (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- Mount Sinai Hospital (US)
- Anna Needs Neuroblastoma Answers (US)
- Hôpital Bichat-Claude-Bernard (FR)
- Imperial College London (GB)
- University of Colorado Anschutz Medical Campus (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Circulation Heart Failure
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1161/circheartfailure.125.013054
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 30.73