Semen Parameter Response to Varicocele Repair in Infertile Men With Cryptozoospermia

Greater than half of the men with cryptozoospermia that underwent varicocele repair improved semen parameters to be optimized for in vitro fertilization/intracytoplasmic sperm injection or potentially lesser involved fertility treatments and obviated the need for surgical sperm retrieval. Neither patient age, serum follicle-stimulating hormone level, nor clinical grade of varicocele showed a statistically significant association with favorable vs unfavorable semen parameter response to varicocele repair in infertile men with preoperative cryptozoospermia. These data suggest that varicocele repair may be offered to infertile, cryptozoospermic men with palpable varicoceles.

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Publication Details

Journal
The Journal of Urology
Published
2026-01-21
DOI
https://doi.org/10.1097/ju.0000000000004944
Primary Topic
Sperm and Testicular Function
Type
article
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article

Semen Parameter Response to Varicocele Repair in Infertile Men With Cryptozoospermia

Romtin Mehrabani-Farsi, A. Farahi, Parviz K. Kavoussi, Shahryar K. Kavoussi et al.
The Journal of Urology
Sperm and Testicular Function
article

Semen Parameter Response to Varicocele Repair in Infertile Men With Cryptozoospermia

Romtin Mehrabani-Farsi, A. Farahi, Parviz K. Kavoussi, Shahryar K. Kavoussi, Negar Farzaneh, Jeissen Pyo, Jason Weiss, Parker R Brown, Laurel Foster, Lauren E Myers, Robert B Sloan
article en

Abstract

Greater than half of the men with cryptozoospermia that underwent varicocele repair improved semen parameters to be optimized for in vitro fertilization/intracytoplasmic sperm injection or potentially lesser involved fertility treatments and obviated the need for surgical sperm retrieval. Neither patient age, serum follicle-stimulating hormone level, nor clinical grade of varicocele showed a statistically significant association with favorable vs unfavorable semen parameter response to varicocele repair in infertile men with preoperative cryptozoospermia. These data suggest that varicocele repair may be offered to infertile, cryptozoospermic men with palpable varicoceles.

The Journal of Urology
Baylor University (US), University of Michigan (US), Scott & White Memorial Hospital (US), Texas Fertility Center (US), The University of Texas at Austin (US), The University of Texas Health Science Center at Houston (US), Bryan College (US)
Zero hunger
Openalex Percentile: Top 82%
Sperm and Testicular Function
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Semen Parameter Response to Varicocele Repair in Infertile Men With Cryptozoospermia — Romtin Mehrabani-Farsi, A. Farahi, et al. · The Journal of Urology (2026) | TGRS Research Map | TGRS