Association between sleep apnea-specific novel hypoxic metrics and disturbances in glucose and lipid metabolism

pRED_3p and SBII were associated not only with established glucose and lipid metabolism parameters-including elevated FBG, FIN, HOMA-IR, hypercholesterolemia, hypertriglyceridemia, and elevated LDL-C-but also with composite lipid indices, exhibiting consistent linear trends. Greater OSA severity corresponded to more marked disturbances in glucose and lipid metabolism. These novel hypoxic metrics may serve as predictive indicators for metabolic dysregulation in OSA.