Early T-Lymphocyte Depletion Predicts Mortality in Critically Ill Children With Severe Infections: An Exploratory Analysis of Cytokine Pathways
Early T cell depletion independently predicts mortality in critically ill children with severe infections. These findings support the prognostic value of early immune profiling and suggest a potential immunoregulatory role for PDGF-AA.
Authors
- Tingyan Liu (ORCID: https://orcid.org/0000-0001-9188-3694)
- Xuemei Zhu
- Hetian Zhou
- C F Zhang
- Kexin Wang (ORCID: https://orcid.org/0000-0002-8541-7512)
- Zimei Cheng (ORCID: https://orcid.org/0000-0002-3994-8339)
- Reyihangu Awuti
- Yixue Wang
- Jinxin Wang
- Lu Guoping
- Weiming Chen
- Yi Zhang
- Yaodong Wang
Institutions
- Anhui Medical University (CN)
- Fudan University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Children's Hospital of Fudan University (CN)
- Children’s Hospital of Fudan University Xiamen Branch (CN)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1097/ccm.0000000000007032
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00