3-Nitrotyrosine activates excitatory interneurons by inhibiting GABA receptors in the rat spinal dorsal horn
3-Nitrotyrosine increases spontaneous glutamate release from the presynaptic terminal to spinal dorsal horn neurons by inhibiting GABA receptors on excitatory interneurons, which in turn enhances their activity.
Authors
- Yuta Yamamoto (ORCID: https://orcid.org/0000-0001-6129-9745)
- Manabu D. Yamanaka (ORCID: https://orcid.org/0000-0002-6776-5150)
- Takeru Ueno (ORCID: https://orcid.org/0009-0008-7776-4515)
- Wataru Taniguchi
- Terumasa Nakatsuka
- Yuta Kaimochi
- Naoko Nishio
- Yuki Matsuyama
- Ryo Miyake
- Hiroshi Yamada
Institutions
- Wakayama Medical University (JP)
- Kansai University (JP)
Publication Details
- Journal
- PAIN Reports
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1097/pr9.0000000000001376
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00