Hypertransaminasemia in a patient with acute abdominal pain: an unusual case report

Hypertransaminasaemia and abdominal pain, although common and non-specific findings, may conceal rare systemic conditions such as IgG4-related disease.Multisystem involvement together with markedly elevated serum IgG4 levels are key clues that should prompt consideration of IgG4-related disease.Early recognition of IgG4-related disease allows timely initiation of immunosuppressive therapy, which is essential to prevent irreversible organ damage.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2026-01-22
DOI
https://doi.org/10.12890/2026_006003
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
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article

Hypertransaminasemia in a patient with acute abdominal pain: an unusual case report

Mauro Giordano, Romeo Morelli, Fabrizio Palumbo, Antonia Ida Facciuto et al.
European Journal of Case Reports in Internal Medicine
IgG4-Related and Inflammatory Diseases
article

Hypertransaminasemia in a patient with acute abdominal pain: an unusual case report

Mauro Giordano, Romeo Morelli, Fabrizio Palumbo, Antonia Ida Facciuto, Martina Finelli, Carmine Nasta, on behalf of the Hypertransaminasemia Study Group, Aurelia Marquardt
article en

Abstract

Hypertransaminasaemia and abdominal pain, although common and non-specific findings, may conceal rare systemic conditions such as IgG4-related disease.Multisystem involvement together with markedly elevated serum IgG4 levels are key clues that should prompt consideration of IgG4-related disease.Early recognition of IgG4-related disease allows timely initiation of immunosuppressive therapy, which is essential to prevent irreversible organ damage.

European Journal of Case Reports in Internal MedicineVol. 13(2)
University of Campania "Luigi Vanvitelli" (IT)
Reduced inequalities
Openalex Percentile: Top 82%
IgG4-Related and Inflammatory Diseases
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