A Transdiagnostic Study of Electroconvulsive Therapy (ECT) Response in Patients with Different Indications for Repeat ECT Courses

Changes in ECT indications between courses suggested a poorer prognosis, but those who showed improvement in global illness severity and quality-of-life tended to experience similar benefits in subsequent ECT courses. Given the lack of correlation between symptom-specific early response across courses, a poor early response in a previous ECT course should not preclude patients from future ECT when clinically indicated.