Endoscopic endonasal approach for craniopharyngioma resection in 604 cases: tumor classification, treatment strategies, and surgical outcomes

The EEA could be considered the first-line surgical treatment modality for most adult and pediatric patients with CP. For large CPs invading the hypothalamus, the EEA allows for sharp dissection of the tumor from the hypothalamus under direct visualization, enabling complete resection while minimizing hypothalamic damage. Intraoperative VEP monitoring aids in reducing visual deterioration. The proposed tumor classification and experience can enhance surgical quality, reduce complications, and guide patient counseling.

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Publication Details

Journal
Journal of neurosurgery
Published
2025-12-01
DOI
https://doi.org/10.3171/2025.8.jns251041
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Endoscopic endonasal approach for craniopharyngioma resection in 604 cases: tumor classification, treatment strategies, and surgical outcomes

Kefan Cai, Changli Liu, Chuzhong Li, Xia Liu et al.
Journal of neurosurgery
Pituitary Gland Disorders and Treatments
article

Endoscopic endonasal approach for craniopharyngioma resection in 604 cases: tumor classification, treatment strategies, and surgical outcomes

Kefan Cai, Changli Liu, Chuzhong Li, Xia Liu, Wentao Wu, Y N Song, Lei Cao, Yazhuo Zhang, Fangzheng Liu, Ning Qiao, Songbai Gui, Haibo Zhu
article en

Abstract

The EEA could be considered the first-line surgical treatment modality for most adult and pediatric patients with CP. For large CPs invading the hypothalamus, the EEA allows for sharp dissection of the tumor from the hypothalamus under direct visualization, enabling complete resection while minimizing hypothalamic damage. Intraoperative VEP monitoring aids in reducing visual deterioration. The proposed tumor classification and experience can enhance surgical quality, reduce complications, and guide patient counseling.

Journal of neurosurgery
Capital Medical University (CN), Beijing Tian Tan Hospital (CN), Beijing Institute of Neurosurgery (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 27%
Pituitary Gland Disorders and Treatments
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Endoscopic endonasal approach for craniopharyngioma resection in 604 cases: tumor classification, treatment strategies, and surgical outcomes — Kefan Cai, Changli Liu, et al. · Journal of neurosurgery (2025) | TGRS Research Map | TGRS