Remote Assessment of Ataxia Severity in <scp>SCA3</scp> Across Multiple Centers and Time Points
SARA<sup>home</sup> is a feasible, innovative video-based tool for remote, high-frequency monitoring of ataxia severity. A 4-day recording effectively captures relevant fluctuations and enhances sensitivity to change, supporting its use in future SCA3 trials.
Authors
- Arian Taheri Amin (ORCID: https://orcid.org/0000-0002-3532-7383)
- Lisa Graf
- Andreas Thieme
- T. Klockgether
- M. João Lima
- Magda Magnolia Santana
- Tamara Schaprian
- Jennifer A Faber
- A. Isabel Ferreira
- Héctor García‐Moreno
- Katharina Hill
- Vivian Maas
- Elin Haf Davis
- Heike Jacobi
- Matthis Synofzik
- Marcus Grobe‐Einsler
- Jeannette Hübener‐Schmid
- Bart P. van de Warrenburg
- Paola Giunti
- Ilse H. J. Willemse
- Dagmar Timmann
Institutions
- Universidade dos Açores (PT)
- Radboud University Nijmegen (NL)
- Eli Lilly (United States) (US)
- Universidade do Porto (PT)
- Heidelberg University (DE)
- University Hospital Bonn (DE)
- German Center for Neurodegenerative Diseases (DE)
- University Hospital Heidelberg (DE)
- Radboud University Medical Center (NL)
- Gene PreDiT (Portugal) (PT)
- Essen University Hospital (DE)
- UK Dementia Research Institute (GB)
- Hertie Institute for Clinical Brain Research (DE)
- Heinrich Heine University Düsseldorf (DE)
- University College London (GB)
- University of Duisburg-Essen (DE)
- University of Coimbra (PT)
- University of Tübingen (DE)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1002/acn3.70316
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Ataxia Foundation
- Eli Lilly and Company
- EU Joint Programme – Neurodegenerative Disease Research
- Ataxia UK
- Bundesministerium für Bildung und Forschung
- Medical Research Council