The therapeutic effects of ligustilide in cuprizone-induced sciatic nerve injury in rats via activation of autophagy and inhibition of apoptosis

Ligustilide has demonstrated significant therapeutic effects in rat models of sciatic nerve injury. It enhances autophagy and inhibits fibrosis and apoptosis.

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Publication Details

Journal
Physiology International
Published
2026-01-22
DOI
https://doi.org/10.1556/2060.2025.00715
Primary Topic
Traditional Chinese Medicine Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

The therapeutic effects of ligustilide in cuprizone-induced sciatic nerve injury in rats via activation of autophagy and inhibition of apoptosis

Mohammed M.H. Al-Gayyar, Malek Alharbi, Shatha S. Alharbi, Abdulazez N. Alqhtani et al.
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Traditional Chinese Medicine Analysis
article

The therapeutic effects of ligustilide in cuprizone-induced sciatic nerve injury in rats via activation of autophagy and inhibition of apoptosis

Mohammed M.H. Al-Gayyar, Malek Alharbi, Shatha S. Alharbi, Abdulazez N. Alqhtani, Abdulrhman A. Eid, Waseem K. Bin Nouh, Meshal M. Albalawi, Hanan M. Hassan, Wejdan M.A. Alghamdi
article en

Abstract

Ligustilide has demonstrated significant therapeutic effects in rat models of sciatic nerve injury. It enhances autophagy and inhibits fibrosis and apoptosis.

Physiology InternationalVol. 113(1)
Mansoura University (EG), University of Tabuk (SA), Delta University for Science and Technology (EG)
Openalex Percentile: Top 80%
Traditional Chinese Medicine Analysis
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