Proportion, Morbidity, and Mortality of Acute Invasive Fungal Rhinosinusitis in Immunocompromised Populations
This systematic review and meta-analysis suggests that the pooled proportion of AIFRS among immunocompromised patients has increased while mortality has declined, reflecting advances in diagnostic and therapeutic approaches. Early detection and aggressive management remain critical to improving outcomes.
Authors
- Cynthia Chelf (ORCID: https://orcid.org/0000-0003-1767-7440)
- Srivatsa Surya Vasudevan (ORCID: https://orcid.org/0000-0002-6998-1658)
- Estephanía Candelo (ORCID: https://orcid.org/0000-0003-3002-7071)
- Angela M. Donaldson (ORCID: https://orcid.org/0000-0002-1442-087X)
- Abigail Verez
- Jorge Abello-Vaamonde
- Alaa Alhalabi
- Gene C. Osuoha
- Byron A. Ward
- Oriana Arias-Valderrama
- Isaac Elijah
Institutions
- Florida State University (US)
- Mayo Clinic (US)
- University of Washington (US)
- Jacksonville College (US)
- Fundación Valle del Lili (CO)
- Universidad Anáhuac (MX)
- Mayo Clinic in Florida (US)
- Morehouse School of Medicine (US)
- Florida Atlantic University (US)
- Icesi University (CO)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1001/jamaoto.2025.5077
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00