In Vitro Antimicrobial Effect of Tetrahydrocannabinol on Streptococcus mutans and Its Anticariogenic Potential
This study shows that THC inhibits S mutans growth, biofilm formation, properties of preformed biofilms, and acid production. It provides preliminary scientific evidence on the impact of THC on oral health, specifically cannabinoid consumption on cariogenesis, and a potential new avenue for developing a new anticariogenic agent.
Authors
- Haoyan Zhai (ORCID: https://orcid.org/0000-0003-2787-937X)
- Joseph Ferracciolo
- Xintian Zhou
- Chunyan Liu
- Eric Krukonis
- Zheng Zhou
- Yixuan Zhang
- Minki Kim
Institutions
- Hebei Medical University (CN)
- University of Detroit Mercy (US)
Publication Details
- Journal
- International Dental Journal
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1016/j.identj.2025.109386
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00