Menstrual blood-derived mesenchymal stromal cell secretome modulates macrophage polarization in a preconditioning-dependent manner
These findings extend the knowledge on the immunomodulatory capacity of the S-MenSC, supporting that MenSCs, particularly when preconditioned, may play a significant role in regulating macrophage polarization, and, thus, modulating the inflammatory response.
Authors
- Ana María Marchena
- María Pulido (ORCID: https://orcid.org/0000-0002-9126-7047)
- Silke Reinartz (ORCID: https://orcid.org/0009-0002-2851-193X)
- María Angeles de Pedro
- Elke Pogge von Strandmann (ORCID: https://orcid.org/0000-0003-4785-9165)
- Johannes Graumann (ORCID: https://orcid.org/0000-0002-3015-5850)
- Francisco M. Sánchez‐Margallo (ORCID: https://orcid.org/0000-0003-2138-988X)
- Witold Szymański (ORCID: https://orcid.org/0000-0002-1202-3299)
- Francisco Manuel González-Nuño
- Johanna Pörschke
- Esther López
- Verónica Álvarez
Institutions
- Philipps University of Marburg (DE)
- Abterra Biosciences (United States) (US)
- Centro de Cirugía de Mínima Invasión Jesús Usón (ES)
- Translational Research in Oncology (FR)
- National Center for Tumor Diseases (DE)
- Research Network (United States) (US)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2026-01-22
- DOI
- https://doi.org/10.3389/fcell.2025.1691010
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00