Complete lymph node dissection versus selective lymph node extirpation in melanoma patients with nodal macrometastasis and adjuvant systemic therapy

CLND showed no OS benefit compared to LNE, while local control was improved. CLND can be recommended in the context of adjuvant therapies, however, the increased rate of complications should be considered.

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Publication Details

Journal
JDDG Journal der Deutschen Dermatologischen Gesellschaft
Published
2026-01-21
DOI
https://doi.org/10.1111/ddg.15967
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Complete lymph node dissection versus selective lymph node extirpation in melanoma patients with nodal macrometastasis and adjuvant systemic therapy

C. Berking, Julia Oberschmied, Kristine E. Mayer, Dirk Tomsitz et al.
JDDG Journal der Deutschen Dermatologischen Gesellschaft
Cutaneous Melanoma Detection and Management
article

Complete lymph node dissection versus selective lymph node extirpation in melanoma patients with nodal macrometastasis and adjuvant systemic therapy

C. Berking, Julia Oberschmied, Kristine E. Mayer, Dirk Tomsitz, Alexander Thiem, Tilo Biedermann, Jannik Sambale, Mihaela‐Anca Sindrilaru, Max Schlaak, Jana Knuever, Christian Posch, Oana‐Diana Persa, Jessica C. Hassel, Michael Erdmann
article en

Abstract

CLND showed no OS benefit compared to LNE, while local control was improved. CLND can be recommended in the context of adjuvant therapies, however, the increased rate of complications should be considered.

JDDG Journal der Deutschen Dermatologischen Gesellschaft
Sigmund Freud Privatuniversität Wien (AT), University of Cologne (DE), Heidelberg University (DE), University Hospital Bonn (DE), University Hospital Heidelberg (DE), LMU Klinikum (DE), National Center for Tumor Diseases (DE), Wiener Krankenanstaltenverbund (AT), Universitätsmedizin Rostock (DE), Centrum für Integrierte Onkologie (DE), Comprehensive Cancer Center Erlangen (DE), University Hospital Ulm (DE), Technical University of Munich (DE), Charité - Universitätsmedizin Berlin (DE), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 81%
Cutaneous Melanoma Detection and Management
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Complete lymph node dissection versus selective lymph node extirpation in melanoma patients with nodal macrometastasis and adjuvant systemic therapy — C. Berking, Julia Oberschmied, et al. · JDDG Journal der Deutschen Dermatologischen Gesellschaft (2026) | TGRS Research Map | TGRS