Comparative Evaluation of Intraperitoneal Instillation of Bupivacaine With Magnesium Sulfate Versus Bupivacaine With Dexmedetomidine for Postoperative Relief After Laparoscopic Cholecystectomy

Intraperitoneal instillation of bupivacaine with magnesium sulfate provides superior early postoperative analgesia compared to bupivacaine with dexmedetomidine, while both combinations are safe and effective. Magnesium sulfate is a cost-effective, readily available adjuvant that may be considered a better alternative in multimodal analgesia for LC.

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Publication Details

Journal
Cureus
Published
2026-01-22
DOI
https://doi.org/10.7759/cureus.102057
Primary Topic
Anesthesia and Pain Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative Evaluation of Intraperitoneal Instillation of Bupivacaine With Magnesium Sulfate Versus Bupivacaine With Dexmedetomidine for Postoperative Relief After Laparoscopic Cholecystectomy

Navneet Gupta, Subhash Dahiya, Jyothi Chaudhary, Garima Luthra et al.
Cureus
Anesthesia and Pain Management
article

Comparative Evaluation of Intraperitoneal Instillation of Bupivacaine With Magnesium Sulfate Versus Bupivacaine With Dexmedetomidine for Postoperative Relief After Laparoscopic Cholecystectomy

Navneet Gupta, Subhash Dahiya, Jyothi Chaudhary, Garima Luthra, Aditi R Singh, Namrata Kaka
article en

Abstract

Intraperitoneal instillation of bupivacaine with magnesium sulfate provides superior early postoperative analgesia compared to bupivacaine with dexmedetomidine, while both combinations are safe and effective. Magnesium sulfate is a cost-effective, readily available adjuvant that may be considered a better alternative in multimodal analgesia for LC.

CureusVol. 18(1)
Lala Lajpat Rai Memorial Medical College (IN)
Good health and well-being
Openalex Percentile: Top 81%
Anesthesia and Pain Management
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