Hyperpigmentation in an Infant due to Vitamin <scp>B12</scp> Deficiency: Case Report

Learning Points Vitamin B12 deficiency in infants may present with neurologic and rare cutaneous signs such as distal hyperpigmentation. Maternal vegetarian or vegan diets during pregnancy and lactation increase the risk of infantile B12 deficiency. Early recognition and treatment with intramuscular hydroxocobalamin can prevent irreversible neurodevelopmental sequelae.

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Publication Details

Journal
Journal of Paediatrics and Child Health
Published
2026-01-21
DOI
https://doi.org/10.1111/jpc.70294
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Hyperpigmentation in an Infant due to Vitamin B12 Deficiency: Case Report

Carmen Malca Gomez, Luis Zavaleta Medina, Miriam Arredondo‐Nontol, Edward Vertiz Barrantes
Journal of Paediatrics and Child Health
Folate and B Vitamins Research
article

Hyperpigmentation in an Infant due to Vitamin B12 Deficiency: Case Report

Carmen Malca Gomez, Luis Zavaleta Medina, Miriam Arredondo‐Nontol, Edward Vertiz Barrantes
article en

Abstract

Learning Points Vitamin B12 deficiency in infants may present with neurologic and rare cutaneous signs such as distal hyperpigmentation. Maternal vegetarian or vegan diets during pregnancy and lactation increase the risk of infantile B12 deficiency. Early recognition and treatment with intramuscular hydroxocobalamin can prevent irreversible neurodevelopmental sequelae.

Journal of Paediatrics and Child HealthVol. 62(3)
Antenor Orrego Private University (PE), Institute of Health Research, Epidemiological Surveillance and Training (SN), EsSALUD (PE), Universidad Nacional de Tumbes (PE)
Zero hunger
Openalex Percentile: Top 82%
Folate and B Vitamins Research
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