Case Report: Extensive colonic necrosis and perforation in an HIV patient with syphilis complicated by sepsis

This case illustrates the rare occurrence of extensive necrosis and perforation of the colon in an HIV-infected patient with co-occurring syphilis. Although the precise role of syphilis in the development of gastrointestinal complications remains uncertain, this case highlights the need for heightened clinical awareness of co-infections in immunocompromised patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-22
DOI
https://doi.org/10.3389/fmed.2025.1687800
Primary Topic
HIV-related health complications and treatments
Type
article
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article

Case Report: Extensive colonic necrosis and perforation in an HIV patient with syphilis complicated by sepsis

Chuan Qian, Sijia Yu, Shouxin Wei
Frontiers in Medicine
HIV-related health complications and treatments
article

Case Report: Extensive colonic necrosis and perforation in an HIV patient with syphilis complicated by sepsis

Chuan Qian, Sijia Yu, Shouxin Wei
article en

Abstract

This case illustrates the rare occurrence of extensive necrosis and perforation of the colon in an HIV-infected patient with co-occurring syphilis. Although the precise role of syphilis in the development of gastrointestinal complications remains uncertain, this case highlights the need for heightened clinical awareness of co-infections in immunocompromised patients.

Frontiers in MedicineVol. 12
Suizhou Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 84%
HIV-related health complications and treatments
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Case Report: Extensive colonic necrosis and perforation in an HIV patient with syphilis complicated by sepsis — Chuan Qian, Sijia Yu, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS