Case Report: Neuroretinitis versus hypertensive retinopathy secondary to Alport syndrome

We consider the possibility of hypertensive retinopathy or idiopathic neuroretinitis in this patient with Alport syndrome. Given the disproportionate degree of macular edema and prominent macular star, in the absence of common manifestations of hypertensive retinopathy such as retinal hemorrhages or hard exudates, we suspect a possible superimposed neuroretinitis-like exudative mechanism driven by the absence of type IV collagen, providing structural support in Alport syndrome patients. This complex symptom presentation, to our knowledge, has never been described in the context of Alport syndrome. Further research is needed to better understand the relationship between Alport-related renal disease, hypertensive retinopathy, and neuroretinitis.