Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium

Elevated pre-Fontan mean pulmonary arterial pressure is a strong predictor of in-hospital and long-term post-Fontan risk of death or transplantation. Systemic right ventricle and delayed Fontan completion (>4 years of age) further increased risk. These findings support early Fontan consideration and ongoing hemodynamic surveillance to optimize long-term outcomes.

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Publication Details

Journal
Circulation
Published
2026-01-22
DOI
https://doi.org/10.1161/circulationaha.125.076880
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium

Asaad G. Beshish, Gurumurthy Hiremath, Rajiv Devanagondi, Yuan Yang et al.
Circulation
Congenital Heart Disease Studies
article

Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium

Asaad G. Beshish, Gurumurthy Hiremath, Rajiv Devanagondi, Yuan Yang, Y. Huang, Divya Suthar, Fawwaz R. Shaw, M. K. Gaitonde, B Marino, Anitha S. John, Kimberly E. McHugh, B. Alsoufi, James D. St. Louis, Lydia Wright, Shriprasad R. Deshpande, Hua Hao, Xiao Song, Matthew E. Oster, Jessica Knight, Geetha Raghuveer, Jeffrey P. Jacobs, Amanda Thomas, Kathy Jenkins, Alvaro Alonso, Charles Canter, David M. Overman
article en

Abstract

Elevated pre-Fontan mean pulmonary arterial pressure is a strong predictor of in-hospital and long-term post-Fontan risk of death or transplantation. Systemic right ventricle and delayed Fontan completion (>4 years of age) further increased risk. These findings support early Fontan consideration and ongoing hemodynamic surveillance to optimize long-term outcomes.

CirculationVol. 153(6)
University of Iowa (US), Boston Children's Hospital (US), University of Minnesota (US), Nationwide Children's Hospital (US), Cleveland Clinic (US), St. Louis Children's Hospital (US), Children’s Minnesota - St. Paul Hospital (US), Children's National (US), Emory University (US), Medical University of South Carolina (US), University of Georgia (US), Augusta University (US), University of Florida (US), Kosair Children's Hospital (US), Norton Hospital (US), Children's Minnesota (US), Children's Healthcare of Atlanta (US), Boston Children's Museum (US), University of Missouri–Kansas City (US), The University of Texas Southwestern Medical Center (US), Florida College (US)
Good health and well-being
Openalex Percentile: Top 81%
Congenital Heart Disease Studies
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