Systemic inflammation is a risk factor for oral health: an analysis of data from the UK Biobank
Our findings support systemic inflammation-mediated via IL-6 signaling-as a causal determinant of impaired oral health. This study provides novel evidence for a directional link from systemic inflammation to oral disease, with potential implications for targeted immunomodulatory interventions in oral health.
Authors
- M. Wolf
- Ulrike Schulze-Späte
- Katharina Marx-Schütt
- Stefan Wolfart
- Nikolaus Marx
- Martin Berger
- Joachim Jankowski
- Jaana-Sophia Kern
Institutions
- Jena University Hospital (DE)
- Westfälische Hochschule (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1651947
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00