Altered gut fungal microbiota and associated mycotoxins in juvenile rat offspring induced by maternal immune activation with Poly I:C

Our findings suggest that MIA-induced behavioral deficits in offspring are accompanied by sex-specific disruptions in gut fungal composition and mycotoxin metabolism, which highlights the need for further intervention studies to establish causality and elucidate the underlying mechanisms of gut fungi and mycotoxins in NDDs.

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Publication Details

Journal
Frontiers in Neuroscience
Published
2026-01-22
DOI
https://doi.org/10.3389/fnins.2026.1702092
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Altered gut fungal microbiota and associated mycotoxins in juvenile rat offspring induced by maternal immune activation with Poly I:C

Yanfang Lu, Fuchun Zhong, Huiyu Chen, Zhenju Cao et al.
Frontiers in Neuroscience
Gut microbiota and health
article

Altered gut fungal microbiota and associated mycotoxins in juvenile rat offspring induced by maternal immune activation with Poly I:C

Yanfang Lu, Fuchun Zhong, Huiyu Chen, Zhenju Cao, Wenjun Lin, Lirong Yang, yueqing su, Xinyu Yang, Fei Xue, Shuangyan Yang, Anying Shen, Menglu Zeng
article en

Abstract

Our findings suggest that MIA-induced behavioral deficits in offspring are accompanied by sex-specific disruptions in gut fungal composition and mycotoxin metabolism, which highlights the need for further intervention studies to establish causality and elucidate the underlying mechanisms of gut fungi and mycotoxins in NDDs.

Frontiers in NeuroscienceVol. 20
Fujian Medical University (CN)
University of Wollongong, Fujian Medical University
Good health and well-being
Openalex Percentile: Top 81%
Gut microbiota and health
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