Circulating Neutrophil and Monocyte Counts Are Inversely Associated With Heart Rate Variability Indices: The Maastricht Study
Higher neutrophil and monocyte counts were associated with lower HRV, irrespective of sex and glucose metabolism status. This suggests a role of these cells reflecting innate immune processes and inflammatory response in cardiac autonomic nervous dysfunction.
Authors
- Anke Wesselius (ORCID: https://orcid.org/0000-0003-4474-9665)
- DAN ZIEGLER
- Nicolaas C. Schaper (ORCID: https://orcid.org/0000-0002-2128-8029)
- Kolade Oluwagbemigun (ORCID: https://orcid.org/0000-0002-9454-5970)
- Coen D.A. Stehouwer (ORCID: https://orcid.org/0000-0001-8752-3223)
- Pieter C. Dagnelie (ORCID: https://orcid.org/0000-0003-1767-8814)
- Marleen M. J. van Greevenbroek (ORCID: https://orcid.org/0000-0002-2989-1631)
- Haïfa Maalmi (ORCID: https://orcid.org/0000-0002-2910-1142)
- Jordi Heijman
- Bastiaan E. de Galan
- Kristiaan Wouters
- Anna Zhu
- Michael Roden
- Carla J. H. van der Kallen
Institutions
- Radboud University Nijmegen (NL)
- Medical University of Graz (AT)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- Cardiovascular Institute Hospital (JP)
- Maastricht University (NL)
- Düsseldorf University Hospital (DE)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1161/jaha.125.043994
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00