Safety and anti-inflammatory activity of Gentiana lutea L. in human bronchial epithelial cell cultures

An aqueous G. lutea root extract is safe to use and exhibits direct anti-inflammatory effects in bronchial epithelial tissues in vitro. These findings provide the first experimental support of its traditional use in respiratory diseases and warrant further preclinical and clinical evaluation.

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Publication Details

Journal
Journal of Ethnopharmacology
Published
2026-01-22
DOI
https://doi.org/10.1016/j.jep.2026.121254
Primary Topic
Phytochemistry and Biological Activities
Type
article
Field-Weighted Citation Impact
0.00
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article

Safety and anti-inflammatory activity of Gentiana lutea L. in human bronchial epithelial cell cultures

Alke Petri‐Fink, Bedia Begüm Karakoçak, Benedikt Maria Huber, Johannes Wildhaber et al.
Journal of Ethnopharmacology
Phytochemistry and Biological Activities
article

Safety and anti-inflammatory activity of Gentiana lutea L. in human bronchial epithelial cell cultures

Alke Petri‐Fink, Bedia Begüm Karakoçak, Benedikt Maria Huber, Johannes Wildhaber, Joanne Wildhaber, Barbara Rothen-Rutishauser, Mauro Sousa de Almeida
article en

Abstract

An aqueous G. lutea root extract is safe to use and exhibits direct anti-inflammatory effects in bronchial epithelial tissues in vitro. These findings provide the first experimental support of its traditional use in respiratory diseases and warrant further preclinical and clinical evaluation.

Journal of EthnopharmacologyVol. 361
University of Fribourg (CH), Fribourg Development Agency (CH), Adolphe Merkle Institute (CH)
Good health and well-being
Openalex Percentile: Top 81%
Phytochemistry and Biological Activities
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