Early intervention in anxiety disorder patients with clinical high-risk factors for bipolar disorder: A randomized controlled trial

This current double-blind, case-controlled study assessed the effectiveness and tolerability of combined therapy <i>vs</i> monotherapy for anxiety disorder in patients with clinical high-risk factors for BD. In light of the constraints associated with this initial study, the results imply that the combination of sertraline and lithium may provide a more favorable prognosis.