A case report of myxoma within the right submandibular muscle and a literature review

Intramuscular myxoma is a rare benign soft-tissue tumor, with an estimated incidence of approximately 0.10-0.13 per 100,000 individuals. Lesions arising in the submandibular muscles are exceptionally uncommon and may be misdiagnosed as sublingual gland cysts. Due to the nonspecific clinical manifestations and potential for misdiagnosis on imaging, histopathological evaluation remains the definitive diagnostic method. Complete surgical excision is the treatment of choice and is generally associated with a favorable prognosis.

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Publication Details

Journal
Frontiers in Surgery
Published
2026-01-22
DOI
https://doi.org/10.3389/fsurg.2025.1733176
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

A case report of myxoma within the right submandibular muscle and a literature review

Y Zhang, RF Zhang, Ye Li, Dingyu Tian et al.
Frontiers in Surgery
Salivary Gland Tumors Diagnosis and Treatment
article

A case report of myxoma within the right submandibular muscle and a literature review

Y Zhang, RF Zhang, Ye Li, Dingyu Tian, Juntao Ma, Xiao Liang
article en

Abstract

Intramuscular myxoma is a rare benign soft-tissue tumor, with an estimated incidence of approximately 0.10-0.13 per 100,000 individuals. Lesions arising in the submandibular muscles are exceptionally uncommon and may be misdiagnosed as sublingual gland cysts. Due to the nonspecific clinical manifestations and potential for misdiagnosis on imaging, histopathological evaluation remains the definitive diagnostic method. Complete surgical excision is the treatment of choice and is generally associated with a favorable prognosis.

Frontiers in SurgeryVol. 12
Dalian Medical University (CN), First Affiliated Hospital of Dalian Medical University (CN)
Openalex Percentile: Top 81%
Salivary Gland Tumors Diagnosis and Treatment
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