Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report
Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, particularly in East Asian countries, despite advances in systemic therapy and the development of novel targeted and immune-based treatments. Due to its aggressive biological behavior, gastric cancer frequently metastasizes to the liver, peritoneum, lymph nodes, lungs and bone. Although extremely rare, pulmonary vein metastasis is clinically significant as it can cause embolic events in vital organs, including multiple cerebral infarctions. The present report describes an extremely rare case of cerebral infarction secondary to pulmonary vein metastasis originating from a gastric adenocarcinoma. To the best of our knowledge, the current case is the first documented case of its kind.
Authors
- Akihiko Yoshizawa (ORCID: https://orcid.org/0000-0003-1462-7341)
- Masatsugu Hamaji (ORCID: https://orcid.org/0000-0002-9808-8260)
- Junichi Takemura
- Masahide OTA
- Nobuhito HARA
- Hitoshi Nakagawa (ORCID: https://orcid.org/0000-0002-1394-8509)
- Yoshiki Kojitani (ORCID: https://orcid.org/0009-0009-6320-5381)
- Shunsuke Okazaki
- Fumi Okada (ORCID: https://orcid.org/0009-0009-0806-5777)
- Mitsuharu Hosono
- Yumi YOSHII
- Rika Sasaki
- Masayuki Takeda
- Ryo Miyata
Institutions
- Nara Medical University (JP)
Publication Details
- Journal
- Oncology Letters
- Published
- 2026-01-22
- DOI
- https://doi.org/10.3892/ol.2026.15469
- Primary Topic
- Metastasis and carcinoma case studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00