Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, particularly in East Asian countries, despite advances in systemic therapy and the development of novel targeted and immune-based treatments. Due to its aggressive biological behavior, gastric cancer frequently metastasizes to the liver, peritoneum, lymph nodes, lungs and bone. Although extremely rare, pulmonary vein metastasis is clinically significant as it can cause embolic events in vital organs, including multiple cerebral infarctions. The present report describes an extremely rare case of cerebral infarction secondary to pulmonary vein metastasis originating from a gastric adenocarcinoma. To the best of our knowledge, the current case is the first documented case of its kind.

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Publication Details

Journal
Oncology Letters
Published
2026-01-22
DOI
https://doi.org/10.3892/ol.2026.15469
Primary Topic
Metastasis and carcinoma case studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Akihiko Yoshizawa, Masatsugu Hamaji, Junichi Takemura, Masahide OTA et al.
Oncology Letters
Metastasis and carcinoma case studies
article

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Akihiko Yoshizawa, Masatsugu Hamaji, Junichi Takemura, Masahide OTA, Nobuhito HARA, Hitoshi Nakagawa, Yoshiki Kojitani, Shunsuke Okazaki, Fumi Okada, Mitsuharu Hosono, Yumi YOSHII, Rika Sasaki, Masayuki Takeda, Ryo Miyata
article en

Abstract

Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, particularly in East Asian countries, despite advances in systemic therapy and the development of novel targeted and immune-based treatments. Due to its aggressive biological behavior, gastric cancer frequently metastasizes to the liver, peritoneum, lymph nodes, lungs and bone. Although extremely rare, pulmonary vein metastasis is clinically significant as it can cause embolic events in vital organs, including multiple cerebral infarctions. The present report describes an extremely rare case of cerebral infarction secondary to pulmonary vein metastasis originating from a gastric adenocarcinoma. To the best of our knowledge, the current case is the first documented case of its kind.

Oncology LettersVol. 31(3)
Nara Medical University (JP)
Good health and well-being
Openalex Percentile: Top 82%
Metastasis and carcinoma case studies
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