Felt Stigma in Youth With Disorders of Gut–Brain Interaction: Implications for Abdominal Pain, Sleep, and Mood

Children with painful disorders of gut-brain interactions (DGBIs) endorse pain-related stigmatization. However, little is known about how stigma may be associated with pain intensity. Consequently, we conducted a cross-sectional study to identify a potential pathway between felt stigma and abdominal pain in youth with DGBIs. 120 youth completed measures of health-related stigma, depressive symptoms, sleep disturbances, and pain severity. As expected, greater felt stigma was significantly correlated with greater depressive symptoms, sleep-related impairments, and abdominal pain. Furthermore, a sequential mediation analysis revealed a significant indirect effect of stigma on abdominal pain via higher depressive symptoms and greater sleep-related impairments. Results suggest potential considerations for modifying current treatments for DGBIs targeting abdominal pain. More specifically, providers should incorporate screening for and addressing felt stigma, sleep-related impairment, and depressive symptoms into their treatment planning. Involving pediatric behavioral health providers may help facilitate this aspect of DGBI intervention.

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Publication Details

Journal
Clinical Pediatrics
Published
2026-01-21
DOI
https://doi.org/10.1177/00099228251415042
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Felt Stigma in Youth With Disorders of Gut–Brain Interaction: Implications for Abdominal Pain, Sleep, and Mood

Aaron D. Fobian, Emily O. Wakefield, Tolulope Adetayo, Marissa A. Gowey et al.
Clinical Pediatrics
Gastrointestinal motility and disorders
article

Felt Stigma in Youth With Disorders of Gut–Brain Interaction: Implications for Abdominal Pain, Sleep, and Mood

Aaron D. Fobian, Emily O. Wakefield, Tolulope Adetayo, Marissa A. Gowey, Corinne T Evans, Demario S. Overstreet, Reed A. Dimmitt, Divya H. Patel, Molly Barr, Burel R. Goodin
article en

Abstract

Children with painful disorders of gut-brain interactions (DGBIs) endorse pain-related stigmatization. However, little is known about how stigma may be associated with pain intensity. Consequently, we conducted a cross-sectional study to identify a potential pathway between felt stigma and abdominal pain in youth with DGBIs. 120 youth completed measures of health-related stigma, depressive symptoms, sleep disturbances, and pain severity. As expected, greater felt stigma was significantly correlated with greater depressive symptoms, sleep-related impairments, and abdominal pain. Furthermore, a sequential mediation analysis revealed a significant indirect effect of stigma on abdominal pain via higher depressive symptoms and greater sleep-related impairments. Results suggest potential considerations for modifying current treatments for DGBIs targeting abdominal pain. More specifically, providers should incorporate screening for and addressing felt stigma, sleep-related impairment, and depressive symptoms into their treatment planning. Involving pediatric behavioral health providers may help facilitate this aspect of DGBI intervention.

Clinical Pediatrics
University of Connecticut (US), Washington University in St. Louis (US), Wallace Community College (US), University of Alabama at Birmingham (US), Connecticut Children's Medical Center (US)
Openalex Percentile: Top 82%
Gastrointestinal motility and disorders
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Felt Stigma in Youth With Disorders of Gut–Brain Interaction: Implications for Abdominal Pain, Sleep, and Mood — Aaron D. Fobian, Emily O. Wakefield, et al. · Clinical Pediatrics (2026) | TGRS Research Map | TGRS