Case Report: Angioimmunoblastic T-cell lymphoma initially diagnosed as eosinophilic granulomatosis with polyangiitis
This case underscores that AITL can closely mimic EGPA, presenting with severe asthma, hypereosinophilia, sinusitis, and systemic symptoms. It emphasizes the necessity of considering underlying lymphoma in patients with suspected EGPA who show an atypical or refractory course to conventional therapy. A definitive diagnosis often requires an adequate tissue sample, preferably from a surgical lymph node biopsy, to avoid misdiagnosis and ensure appropriate management. Respiratory physicians should maintain a high index of suspicion for lymphoid malignancies in such complex presentations.
Authors
- Yi Guo (ORCID: https://orcid.org/0000-0003-0587-4105)
- Rui Dai (ORCID: https://orcid.org/0000-0002-0690-1980)
- Jialing Xie
- Yong Sun (ORCID: https://orcid.org/0000-0003-0511-0308)
- Simin Xie
- Guochao Shi
- Yingmeng Ni
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-22
- DOI
- https://doi.org/10.3389/fmed.2025.1716129
- Primary Topic
- Vascular Tumors and Angiosarcomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00