Effect of different diastolic blood pressure levels on the prognosis of patients with heart failure after acute myocardial infarction

Different DBP levels at discharge in patients with heart failure after AMI are useful for patient prognosis evaluation. Maybe patients with heart failure after AMI with a low DBP (<70 mmHg) at discharge have a lower risk of all-cause mortality and all-cause readmission. Notably, the study population had a relatively high mean left ventricular ejection fraction, and a higher number of patients in the DBP < 70 mmHg group were treated with MRAs. Since MRAs themselves have blood pressure-lowering effects, their use may have influenced the results and prognosis. Therefore, until these findings are confirmed by further trials, active reduction of diastolic blood pressure should be approached with caution. This conclusion requires validation through large-scale randomized studies.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-22
DOI
https://doi.org/10.3389/fcvm.2025.1703466
Primary Topic
Heart Failure Treatment and Management
Type
article
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article

Effect of different diastolic blood pressure levels on the prognosis of patients with heart failure after acute myocardial infarction

Xiao Feng Wang, Zhao Zhigang, Jingyao Wang, Xue Sun et al.
Frontiers in Cardiovascular Medicine
Heart Failure Treatment and Management
article

Effect of different diastolic blood pressure levels on the prognosis of patients with heart failure after acute myocardial infarction

Xiao Feng Wang, Zhao Zhigang, Jingyao Wang, Xue Sun, Mengjie Lei, Zengming Xue, Cairong Li, Chunyan Zhang, Yachao Li, Wanda Ma
article en

Abstract

Different DBP levels at discharge in patients with heart failure after AMI are useful for patient prognosis evaluation. Maybe patients with heart failure after AMI with a low DBP (<70 mmHg) at discharge have a lower risk of all-cause mortality and all-cause readmission. Notably, the study population had a relatively high mean left ventricular ejection fraction, and a higher number of patients in the DBP < 70 mmHg group were treated with MRAs. Since MRAs themselves have blood pressure-lowering effects, their use may have influenced the results and prognosis. Therefore, until these findings are confirmed by further trials, active reduction of diastolic blood pressure should be approached with caution. This conclusion requires validation through large-scale randomized studies.

Frontiers in Cardiovascular MedicineVol. 12
Hebei North University (CN), Langfang Normal University (CN)
Good health and well-being
Openalex Percentile: Top 82%
Heart Failure Treatment and Management
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