Single administration of vitamin C produces rapid antidepressant-like effects in female mice: A possible role of dopamine D2 receptor signalling

Our findings suggest that vitamin C may serve as an ideal candidate for the treatment of depression in females, potentially through the restoration of the D2R-BDNF pathway.

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Publication Details

Journal
Brain Research
Published
2026-01-22
DOI
https://doi.org/10.1016/j.brainres.2026.150181
Primary Topic
Vitamin C and Antioxidants Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Single administration of vitamin C produces rapid antidepressant-like effects in female mice: A possible role of dopamine D2 receptor signalling

Minglian Luo, Xuemei Gao, Yuan-Jian Yang, Yi-Heng Li et al.
Brain Research
Vitamin C and Antioxidants Research
article

Single administration of vitamin C produces rapid antidepressant-like effects in female mice: A possible role of dopamine D2 receptor signalling

Minglian Luo, Xuemei Gao, Yuan-Jian Yang, Yi-Heng Li, Shu-Zhen Jiang
article en

Abstract

Our findings suggest that vitamin C may serve as an ideal candidate for the treatment of depression in females, potentially through the restoration of the D2R-BDNF pathway.

Brain ResearchVol. 1875
Wuhan Puai Hospital (CN), Wuhan No.1 Hospital (CN), Wuhan No. 7 Hospital (CN), Jiangxi Mental Health Center (CN), Wuhan No.9 Hospital (CN)
Good health and well-being
Openalex Percentile: Top 81%
Vitamin C and Antioxidants Research
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