Measuring MMP-7 levels in dried blood spots appears not feasible for newborn screening of biliary atresia
MMP-7 is elevated in BA patients' DBS at birth, but current performance characteristics are insufficient for reliable NBS. Larger studies and multiparametric approaches may be needed to improve screening feasibility.
Authors
- Christian Klemann (ORCID: https://orcid.org/0000-0002-5639-8690)
- Marie Uecker
- Claus Petersen (ORCID: https://orcid.org/0000-0002-1789-7163)
- Nils Janzen (ORCID: https://orcid.org/0000-0002-2313-3311)
- Joachim F. Kuebler
- O. Madadi-Sanjani
- Björn Bulitta
Institutions
- Universität Hamburg (DE)
- Medizinische Hochschule Hannover (DE)
- Kinderkrankenhaus auf der Bult (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University Hospital Leipzig (DE)
- Klinikum Bremen-Mitte (DE)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1097/hc9.0000000000000896
- Primary Topic
- Pediatric Hepatobiliary Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00