Mesenchymal Stem Cell‐Mediated Vascular Regeneration in Diabetic Foot Ulcers via the Notch Signaling Pathway

These findings suggest that MSCs promote DFU healing, and Notch signaling plays a crucial role in enhancing MSC-mediated repair. Our results highlight the potential of MSC-based therapies combined with Notch pathway modulation as a promising strategy for improving DFU treatment and wound healing in diabetic patients.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2026-01-21
DOI
https://doi.org/10.1002/jcla.70162
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
0.00
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article

Mesenchymal Stem Cell‐Mediated Vascular Regeneration in Diabetic Foot Ulcers via the Notch Signaling Pathway

Yuhong Gu, Zuwei Yang, Xin Hou, Jingming Ou et al.
Journal of Clinical Laboratory Analysis
Mesenchymal stem cell research
article

Mesenchymal Stem Cell‐Mediated Vascular Regeneration in Diabetic Foot Ulcers via the Notch Signaling Pathway

Yuhong Gu, Zuwei Yang, Xin Hou, Jingming Ou, Feifei Li, Li Xu, Dengfeng Zhu
article en

Abstract

These findings suggest that MSCs promote DFU healing, and Notch signaling plays a crucial role in enhancing MSC-mediated repair. Our results highlight the potential of MSC-based therapies combined with Notch pathway modulation as a promising strategy for improving DFU treatment and wound healing in diabetic patients.

Journal of Clinical Laboratory AnalysisVol. 40(4)
Shanghai Medical College of Fudan University (CN), Kunming Medical University (CN), Second Affiliated Hospital of Kunming Medical College (CN), XinHua Hospital (CN), Shanghai Medical Information Center (CN)
Good health and well-being
Openalex Percentile: Top 82%
Mesenchymal stem cell research
DOIOpen Access PDFOpenAlex
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