Identification of hypoxia- and mitophagy-related diagnostic biomarkers for ulcerative colitis based on bioinformatic analysis and machine learning

We elucidated the relationship between UC and hypoxia/mitophagy and identified potential diagnostic biomarkers. This study provides a reference for the future development of targeted treatment strategies to improve diagnostic and therapeutic protocols for UC.

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Publication Details

Journal
PLoS ONE
Published
2026-01-21
DOI
https://doi.org/10.1371/journal.pone.0339296
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of hypoxia- and mitophagy-related diagnostic biomarkers for ulcerative colitis based on bioinformatic analysis and machine learning

YuHan Jian, Yuyu Peng, Yuedong Liu, Yangling Huang et al.
PLoS ONE
Autophagy in Disease and Therapy
article

Identification of hypoxia- and mitophagy-related diagnostic biomarkers for ulcerative colitis based on bioinformatic analysis and machine learning

YuHan Jian, Yuyu Peng, Yuedong Liu, Yangling Huang, Lun Zhao, Yu Fu, Yanlin Zhu, Zewei Sheng, Xuefeng Liu
article en

Abstract

We elucidated the relationship between UC and hypoxia/mitophagy and identified potential diagnostic biomarkers. This study provides a reference for the future development of targeted treatment strategies to improve diagnostic and therapeutic protocols for UC.

PLoS ONEVol. 21(1)
Liaoning University of Traditional Chinese Medicine (CN), Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
National Natural Science Foundation of China, Liaoning University, Liaoning University of Traditional Chinese Medicine
Good health and well-being
Openalex Percentile: Top 82%
Autophagy in Disease and Therapy
DOIOpen Access PDFOpenAlex
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Identification of hypoxia- and mitophagy-related diagnostic biomarkers for ulcerative colitis based on bioinformatic analysis and machine learning — YuHan Jian, Yuyu Peng, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS