Pemetrexed sensitizes cisplatin therapy by inducing ferroptosis in NSCLC cells
In summary, these results provide <i>in vitro</i> experimental evidence that PEM boosts the antitumor activity and increases the sensitivity of NSCLC cells to DDP by inducing ferroptosis.
Authors
- J. Chen
- Yuwei Cao (ORCID: https://orcid.org/0000-0003-2284-4223)
- X. Zhang
- Yumin Wang (ORCID: https://orcid.org/0000-0001-8243-3659)
- Y. Zhu
- Yulin Li
- Ge Zhang
Institutions
- King University (US)
- Aerospace Center Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fphar.2025.1764937
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wu Jieping Medical Foundation