Cross-tissue transcriptome-wide association identify novel T1D susceptibility genes and drug candidates

Our study reveals novel genetic associations and immune-related pathways in T1D pathogenesis, and proposes specific genes and compounds as promising focal points for future mechanistic and therapeutic exploration.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-21
DOI
https://doi.org/10.3389/fimmu.2025.1735004
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Cross-tissue transcriptome-wide association identify novel T1D susceptibility genes and drug candidates

Yaohui Jiang, Yalin Liu, Yu Cao
Frontiers in Immunology
Diabetes and associated disorders
article

Cross-tissue transcriptome-wide association identify novel T1D susceptibility genes and drug candidates

Yaohui Jiang, Yalin Liu, Yu Cao
article en

Abstract

Our study reveals novel genetic associations and immune-related pathways in T1D pathogenesis, and proposes specific genes and compounds as promising focal points for future mechanistic and therapeutic exploration.

Frontiers in ImmunologyVol. 16
Central South University (CN), Anhui Medical University (CN), Zhengzhou Central Hospital (CN), First Affiliated Hospital of Anhui Medical University (CN), Third Xiangya Hospital (CN)
Good health and well-being
Openalex Percentile: Top 77%
Diabetes and associated disorders
DOIOpen Access PDFOpenAlex
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