Prevention, diagnosis and management of community acquired respiratory virus infections including COVID-19 in patients with cancer: 2025 updated evidence-based guideline of the infectious diseases working party (AGIHO) of the German society for hemat

Community-acquired respiratory viruses (CARV), such as influenza-, parainfluenza- or respiratory syncytial virus, pose a significant threat to immunocompromised patients with cancer. Following the COVID-19 pandemic, SARS-CoV-2 has now joined the ranks of endemic respiratory viruses and continues to be a cause of significant morbidity and mortality in patients with cancer. Strategies to protect this vulnerable patient population both by prevention of infection and by early therapeutic intervention in case of infectious disease are therefore of utmost importance. This guideline provides updated evidence-based recommendations on diagnosis, prophylaxis and treatment of CARV infections including COVID-19 in patients with solid tumors or hematologic malignancies to support clinicians in offering optimal care. The guideline is based on a systematic review of currently available data and was developed until the beginning of 2025 by an expert panel of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO).

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Publication Details

Journal
Annals of Hematology
Published
2026-01-21
DOI
https://doi.org/10.1007/s00277-026-06769-9
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Prevention, diagnosis and management of community acquired respiratory virus infections including COVID-19 in patients with cancer: 2025 updated evidence-based guideline of the infectious diseases working party (AGIHO) of the German society for hemat

Felix Korell, Marcus Hentrich, Elham Khatamzas, Nicola Giesen et al.
Annals of Hematology
Respiratory viral infections research
article

Prevention, diagnosis and management of community acquired respiratory virus infections including COVID-19 in patients with cancer: 2025 updated evidence-based guideline of the infectious diseases working party (AGIHO) of the German society for hemat

Felix Korell, Marcus Hentrich, Elham Khatamzas, Nicola Giesen, Malte B. Monin, C Heußel, Sebastian Voigt, Daniel Teschner, Sibylle C. Mellinghoff, Hermann Einsele, Marie von Lilienfeld-Toal, Philippe Schafhausen, Björn-Erik Ole Jensen, Christian Hohmann, Larissa Henze, Christina Rieger, Oliver A. Cornely
article en

Abstract

Community-acquired respiratory viruses (CARV), such as influenza-, parainfluenza- or respiratory syncytial virus, pose a significant threat to immunocompromised patients with cancer. Following the COVID-19 pandemic, SARS-CoV-2 has now joined the ranks of endemic respiratory viruses and continues to be a cause of significant morbidity and mortality in patients with cancer. Strategies to protect this vulnerable patient population both by prevention of infection and by early therapeutic intervention in case of infectious disease are therefore of utmost importance. This guideline provides updated evidence-based recommendations on diagnosis, prophylaxis and treatment of CARV infections including COVID-19 in patients with solid tumors or hematologic malignancies to support clinicians in offering optimal care. The guideline is based on a systematic review of currently available data and was developed until the beginning of 2025 by an expert panel of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO).

Annals of HematologyVol. 105(2)
Universität Hamburg (DE), University of Cologne (DE), Heidelberg University (DE), University Hospital Bonn (DE), German Red Cross (DE), University Hospital Heidelberg (DE), Robert Bosch Hospital (DE), LMU Klinikum (DE), Düsseldorf University Hospital (DE), Krankenhaus vom Roten Kreuz (DE), Integrated Oncology (United States) (US), University Medical Center Hamburg-Eppendorf (DE), Universitätsklinikum Knappschaftskrankenhaus Bochum (DE), German Center for Infection Research (DE), Universitätsklinikum Würzburg (DE), German Center for Lung Research (DE), Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (DE), St. Josef-Hospital (DE), Asklepios Klinikum Harburg (DE), Klinikum Bremen-Mitte (DE), University Hospital Cologne (DE), Agaplesion Diakonieklinikum Rotenburg (DE), Heinrich Heine University Düsseldorf (DE), University of Rostock (DE), University of Duisburg-Essen (DE), Ludwig-Maximilians-Universität München (DE), Ruhr University Bochum (DE), Otto-von-Guericke-Universität Magdeburg (DE)
Good health and well-being
Openalex Percentile: Top 82%
Respiratory viral infections research
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